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KLF4 Regulates Goblet Cell Differentiation in BMI1(+) Reserve Intestinal Stem Cell Lineage during Homeostasis
Krüppel-like factor 4 (KLF4) is a zinc-finger transcription factor, expressed in villus cells of the intestinal epithelium, that promotes cellular differentiation and tissue homeostasis. Previous studies suggest that BMI1(+) cells represent secretory progenitors with reserve intestinal stem cell (rI...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society for Stem Cell Research
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691855/ https://www.ncbi.nlm.nih.gov/pubmed/32840226 http://dx.doi.org/10.15283/ijsc20048 |