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Cdo Is Required for Efficient Motor Neuron Generation of Embryonic Stem Cells

BACKGROUND AND OBJECTIVES: The directed differentiation of pluripotent stem cells into motor neurons is critical for the development of disease modelling and therapeutics to intervene degenerative motor neuron diseases. Cell surface receptor Cdo functions as a coreceptor for Sonic hedgehog (Shh) wit...

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Detalles Bibliográficos
Autores principales: Kim, Hyebeen, Lee, Seul-Yi, Jeong, Hyeon-Ju, Kang, Jong-Sun, Cho, Hana, Leem, Young-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691856/
https://www.ncbi.nlm.nih.gov/pubmed/32840224
http://dx.doi.org/10.15283/ijsc20037