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Cell geometry and the cytoskeleton impact the nucleo-cytoplasmic localisation of the SMYD3 methyltransferase

Mechanical cues from the cellular microenvironment are converted into biochemical signals controlling diverse cell behaviours, including growth and differentiation. But it is still unclear how mechanotransduction ultimately affects nuclear readouts, genome function and transcriptional programs. Key...

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Detalles Bibliográficos
Autores principales: Pereira, David, Richert, Alain, Medjkane, Souhila, Hénon, Sylvie, Weitzman, Jonathan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691988/
https://www.ncbi.nlm.nih.gov/pubmed/33244033
http://dx.doi.org/10.1038/s41598-020-75833-9