Direct RNA sequencing reveals m(6)A modifications on adenovirus RNA are necessary for efficient splicing

Adenovirus is a nuclear replicating DNA virus reliant on host RNA processing machinery. Processing and metabolism of cellular RNAs can be regulated by METTL3, which catalyzes the addition of N6-methyladenosine (m(6)A) to mRNAs. While m(6)A-modified adenoviral RNAs have been previously detected, the...

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Detalles Bibliográficos
Autores principales: Price, Alexander M., Hayer, Katharina E., McIntyre, Alexa B. R., Gokhale, Nandan S., Abebe, Jonathan S., Della Fera, Ashley N., Mason, Christopher E., Horner, Stacy M., Wilson, Angus C., Depledge, Daniel P., Weitzman, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691994/
https://www.ncbi.nlm.nih.gov/pubmed/33243990
http://dx.doi.org/10.1038/s41467-020-19787-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691994/
https://www.ncbi.nlm.nih.gov/pubmed/33243990
http://dx.doi.org/10.1038/s41467-020-19787-6

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