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Quantifying PD-L1 Expression to Monitor Immune Checkpoint Therapy: Opportunities and Challenges

SIMPLE SUMMARY: Malignant cells hijack the regulatory roles of immune checkpoint proteins for immune evasion and survival. Therapeutics blocking those proteins can restore the balance of the immune system and lead to durable responses in cancer patients. Although a subset of patients derive benefit,...

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Detalles Bibliográficos
Autor principal: Nimmagadda, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692040/
https://www.ncbi.nlm.nih.gov/pubmed/33137949
http://dx.doi.org/10.3390/cancers12113173