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Modeling Mucopolysaccharidosis Type II in the Fruit Fly by Using the RNA Interference Approach

Mucopolysaccharidosis type II (MPS II) is a lysosomal storage disorder that occurs due to the deficit of the lysosomal enzyme iduronate 2-sulfatase (IDS) that leads to the storage of the glycosaminoglycan heparan- and dermatan-sulfate in all organs and tissues. It is characterized by important clini...

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Detalles Bibliográficos
Autores principales: Rigon, Laura, Kucharowski, Nicole, Eckardt, Franka, Bauer, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692102/
https://www.ncbi.nlm.nih.gov/pubmed/33142967
http://dx.doi.org/10.3390/life10110263