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NOX2ko Mice Show Largely Increased Expression of a Mutated NOX2 mRNA Encoding an Inactive NOX2 Protein

Background: The superoxide-generating enzyme nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX2 or gp91phox, the phagocytic isoform) was reported as a major source of oxidative stress in various human diseases. Genetic deletion is widely used to study the impact of NOX2-derived reacti...

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Detalles Bibliográficos
Autores principales: Göllner, Monika, Ihrig-Biedert, Irmgard, Petermann, Victoria, Saurin, Sabrina, Oelze, Matthias, Kröller-Schön, Swenja, Vujacic-Mirski, Ksenija, Kuntic, Marin, Pautz, Andrea, Daiber, Andreas, Kleinert, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692237/
https://www.ncbi.nlm.nih.gov/pubmed/33114493
http://dx.doi.org/10.3390/antiox9111043