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NOX2ko Mice Show Largely Increased Expression of a Mutated NOX2 mRNA Encoding an Inactive NOX2 Protein
Background: The superoxide-generating enzyme nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX2 or gp91phox, the phagocytic isoform) was reported as a major source of oxidative stress in various human diseases. Genetic deletion is widely used to study the impact of NOX2-derived reacti...
Autores principales: | Göllner, Monika, Ihrig-Biedert, Irmgard, Petermann, Victoria, Saurin, Sabrina, Oelze, Matthias, Kröller-Schön, Swenja, Vujacic-Mirski, Ksenija, Kuntic, Marin, Pautz, Andrea, Daiber, Andreas, Kleinert, Hartmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692237/ https://www.ncbi.nlm.nih.gov/pubmed/33114493 http://dx.doi.org/10.3390/antiox9111043 |
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