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Effects of Pirfenidone and Nintedanib on Markers of Systemic Oxidative Stress and Inflammation in Patients with Idiopathic Pulmonary Fibrosis: A Preliminary Report

Introduction: In vitro evidence suggests that pirfenidone and nintedanib, approved agents for the treatment of idiopathic pulmonary fibrosis (IPF), exert anti-inflammatory and anti-oxidant effects. We aimed to investigate such effects in vivo in IPF patients. Methods: Systemic circulating markers of...

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Detalles Bibliográficos
Autores principales: Fois, Alessandro G., Sotgiu, Elisabetta, Scano, Valentina, Negri, Silvia, Mellino, Sabrina, Zinellu, Elisabetta, Pirina, Pietro, Pintus, Gianfranco, Carru, Ciriaco, Mangoni, Arduino A., Zinellu, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692317/
https://www.ncbi.nlm.nih.gov/pubmed/33143144
http://dx.doi.org/10.3390/antiox9111064