Proteasome Inhibitor MG132 is Toxic and Inhibits the Proliferation of Rat Neural Stem Cells but Increases BDNF Expression to Protect Neurons

Regulation of protein expression is essential for maintaining normal cell function. Proteasomes play important roles in protein degradation and dysregulation of proteasomes is implicated in neurodegenerative disorders. In this study, using a proteasome inhibitor MG132, we showed that proteasome inhi...

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Detalles Bibliográficos
Autores principales: Kim, Young Min, Kim, Hyun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692322/
https://www.ncbi.nlm.nih.gov/pubmed/33147870
http://dx.doi.org/10.3390/biom10111507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692322/
https://www.ncbi.nlm.nih.gov/pubmed/33147870
http://dx.doi.org/10.3390/biom10111507

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