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A Molecular Test for Quantifying Functional Notch Signaling Pathway Activity in Human Cancer

SIMPLE SUMMARY: The Notch signal transduction pathway is important for various physiological processes, including immune responses, and plays a role in many diseases, for example cancer. We have developed a new assay to quantitatively measure Notch pathway activity, and we validated it using data fr...

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Detalles Bibliográficos
Autores principales: Canté-Barrett, Kirsten, Holtzer, Laurent, van Ooijen, Henk, Hagelaar, Rico, Cordo’, Valentina, Verhaegh, Wim, van de Stolpe, Anja, Meijerink, Jules P. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692325/
https://www.ncbi.nlm.nih.gov/pubmed/33120947
http://dx.doi.org/10.3390/cancers12113142