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Effects of Intestinal Microbiota on Pharmacokinetics of Crocin and Crocetin in Male Sprague-Dawley Rats

In addition to the hepatic metabolism, the role of intestinal microbiota in drug metabolism has been considered important in the biotransformation of xenobiotics. Crocin and its aglycone, crocetin, isolated from many plants, including the dried stigma of Crocus sativus and the fruit of Gardenia jasm...

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Detalles Bibliográficos
Autores principales: Shakya, Rajina, Nepal, Mahesh R., Kang, Mi Jeong, Jeong, Tae Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692355/
https://www.ncbi.nlm.nih.gov/pubmed/33114484
http://dx.doi.org/10.3390/metabo10110424