A Single Amino Acid Residue Regulates PTEN-Binding and Stability of the Spinal Muscular Atrophy Protein SMN

Spinal Muscular Atrophy (SMA) is a neuromuscular disease caused by decreased levels of the survival of motoneuron (SMN) protein. Post-translational mechanisms for regulation of its stability are still elusive. Thus, we aimed to identify regulatory phosphorylation sites that modulate function and sta...

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Detalles Bibliográficos
Autores principales: Rademacher, Sebastian, Detering, Nora T., Schüning, Tobias, Lindner, Robert, Santonicola, Pamela, Wefel, Inga-Maria, Dehus, Janina, Walter, Lisa M., Brinkmann, Hella, Niewienda, Agathe, Janek, Katharina, Varela, Miguel A., Bowerman, Melissa, Di Schiavi, Elia, Claus, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692393/
https://www.ncbi.nlm.nih.gov/pubmed/33153033
http://dx.doi.org/10.3390/cells9112405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692393/
https://www.ncbi.nlm.nih.gov/pubmed/33153033
http://dx.doi.org/10.3390/cells9112405

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