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HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection

HIV-1 genetic diversity can be used to infer time since infection (TSI) and infection recency. We adapted this approach for HCV and identified genomic regions with informative diversity. We included 72 HCV/HIV-1 coinfected participants of the Swiss HIV Cohort Study, for whom reliable estimates of in...

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Detalles Bibliográficos
Autores principales: Carlisle, Louisa A., Turk, Teja, Metzner, Karin J., Mbunkah, Herbert A., Shah, Cyril, Böni, Jürg, Huber, Michael, Braun, Dominique L., Fehr, Jan, Salazar-Vizcaya, Luisa, Rauch, Andri, Yerly, Sabine, Nguyen, Aude, Cavassini, Matthias, Stoeckle, Marcel, Vernazza, Pietro, Bernasconi, Enos, Günthard, Huldrych F., Kouyos, Roger D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692400/
https://www.ncbi.nlm.nih.gov/pubmed/33142675
http://dx.doi.org/10.3390/v12111241