Cargando…

HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection

HIV-1 genetic diversity can be used to infer time since infection (TSI) and infection recency. We adapted this approach for HCV and identified genomic regions with informative diversity. We included 72 HCV/HIV-1 coinfected participants of the Swiss HIV Cohort Study, for whom reliable estimates of in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carlisle, Louisa A., Turk, Teja, Metzner, Karin J., Mbunkah, Herbert A., Shah, Cyril, Böni, Jürg, Huber, Michael, Braun, Dominique L., Fehr, Jan, Salazar-Vizcaya, Luisa, Rauch, Andri, Yerly, Sabine, Nguyen, Aude, Cavassini, Matthias, Stoeckle, Marcel, Vernazza, Pietro, Bernasconi, Enos, Günthard, Huldrych F., Kouyos, Roger D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692400/ https://www.ncbi.nlm.nih.gov/pubmed/33142675 http://dx.doi.org/10.3390/v12111241

Ejemplares similares

Changing Trends in International Versus Domestic HCV Transmission in HIV-Positive Men Who Have Sex With Men: A Perspective for the Direct-Acting Antiviral Scale-Up Era
por: Salazar-Vizcaya, Luisa, et al.
Publicado: (2019)

A Phylogeny-aware GWAS Framework to Correct for Heritable Pathogen Effects on Infectious Disease Traits
por: Nadeau, Sarah, et al.
Publicado: (2022)

Impact of Direct-Acting Antivirals on the Burden of HCV Infection Among Persons Who Inject Drugs and Men Who Have Sex With Men in the Swiss HIV Cohort Study
por: Salazar-Vizcaya, Luisa, et al.
Publicado: (2018)

Ambiguous Nucleotide Calls From Population-based Sequencing of HIV-1 are a Marker for Viral Diversity and the Age of Infection
por: Kouyos, Roger D., et al.
Publicado: (2011)

Inferring the age difference in HIV transmission pairs by applying phylogenetic methods on the HIV transmission network of the Swiss HIV Cohort Study
por: Kusejko, Katharina, et al.
Publicado: (2018)

An Approach to Quantifying the Interaction between Behavioral and Transmission Clusters
por: Salazar-Vizcaya, Luisa, et al.
Publicado: (2022)

The Cumulative Impact of Harm Reduction on the Swiss HIV Epidemic: Cohort Study, Mathematical Model, and Phylogenetic Analysis
por: Marzel, Alex, et al.
Publicado: (2018)

Assessing the danger of self-sustained HIV epidemics in heterosexuals by population based phylogenetic cluster analysis
por: Turk, Teja, et al.
Publicado: (2017)

Minor Protease Inhibitor Mutations at Baseline Do Not Increase the Risk for a Virological Failure in HIV-1 Subtype B Infected Patients
por: Scherrer, Alexandra U., et al.
Publicado: (2012)

Early Antiretroviral Therapy During Primary HIV-1 Infection Results in a Transient Reduction of the Viral Setpoint upon Treatment Interruption
por: von Wyl, Viktor, et al.
Publicado: (2011)

The Individualized Genetic Barrier Predicts Treatment Response in a Large Cohort of HIV-1 Infected Patients
por: Beerenwinkel, Niko, et al.
Publicado: (2013)

Predictors of Virological Failure and Time to Viral Suppression of First-Line Integrase Inhibitor–Based Antiretroviral Treatment
por: Pyngottu, Ashima, et al.
Publicado: (2020)

Increases in Condomless Sex in the Swiss HIV Cohort Study
por: Kouyos, Roger D., et al.
Publicado: (2015)

Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL’HIV trial
por: Sculier, Delphine, et al.
Publicado: (2020)

Correction: Long-Lasting Protection of Activity of Nucleoside Reverse Transcriptase Inhibitors and Protease Inhibitors (PIs) by Boosted PI Containing Regimens
por: Scherrer, Alexandra U., et al.
Publicado: (2013)

Long-Lasting Protection of Activity of Nucleoside Reverse Transcriptase Inhibitors and Protease Inhibitors (PIs) by Boosted PI Containing Regimens
por: Scherrer, Alexandra U., et al.
Publicado: (2012)

Genotypic Resistance Tests Sequences Reveal the Role of Marginalized Populations in HIV-1 Transmission in Switzerland
por: Shilaih, Mohaned, et al.
Publicado: (2016)

Phylogenetic Approach Reveals That Virus Genotype Largely Determines HIV Set-Point Viral Load
por: Alizon, Samuel, et al.
Publicado: (2010)

Assessing the drivers of syphilis among men who have sex with men in Switzerland reveals a key impact of screening frequency: A modelling study
por: Balakrishna, Suraj, et al.
Publicado: (2021)

Triggers of Change in Sexual Behavior Among People With HIV: The Swiss U = U Statement and COVID-19 Compared
por: Hamusonde, Kalongo, et al.
Publicado: (2022)

Incident Hepatitis C Virus Infections in the Swiss HIV Cohort Study: Changes in Treatment Uptake and Outcomes Between 1991 and 2013
por: Wandeler, Gilles, et al.
Publicado: (2015)

Replicative phenotyping adds value to genotypic resistance testing in heavily pre-treated HIV-infected individuals - the Swiss HIV Cohort Study
por: Fehr, Jan, et al.
Publicado: (2011)

Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART
por: Wan, Chenjie, et al.
Publicado: (2020)

Adverse events of raltegravir and dolutegravir
por: Elzi, Luigia, et al.
Publicado: (2017)

Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART
por: Bachmann, Nadine, et al.
Publicado: (2019)

Sexual Behaviour and STI Incidence in Sexually Active MSM Living With HIV in Times of COVID-19
por: Mugglin, Catrina, et al.
Publicado: (2023)

Dissecting HIV Virulence: Heritability of Setpoint Viral Load, CD4+ T-Cell Decline, and Per-Parasite Pathogenicity
por: Bertels, Frederic, et al.
Publicado: (2018)

Unsupervised machine learning predicts future sexual behaviour and sexually transmitted infections among HIV-positive men who have sex with men
por: Andresen, Sara, et al.
Publicado: (2022)

Diagnosis of latent tuberculosis infection is associated with reduced HIV viral load and lower risk for opportunistic infections in people living with HIV
por: Kusejko, Katharina, et al.
Publicado: (2020)

Hepatitis C virus transmission among human immunodeficiency virus‐infected men who have sex with men: Modeling the effect of behavioral and treatment interventions
por: Salazar‐Vizcaya, Luisa, et al.
Publicado: (2016)

Minority K65R Variants and Early Failure of Antiretroviral Therapy in HIV-1–infected Eritrean Immigrant
por: Bansal, Vineeta, et al.
Publicado: (2011)

Systematic screening of viral and human genetic variation identifies antiretroviral resistance and immune escape link
por: Nguyen, Huyen, et al.
Publicado: (2021)

Long-term trends of alanine aminotransferase levels among persons living with human immunodeficiency virus/hepatitis B virus with and without hepatitis delta coinfection
por: Begré, Lorin, et al.
Publicado: (2022)

Cohort-Derived Machine Learning Models for Individual Prediction of Chronic Kidney Disease in People Living With Human Immunodeficiency Virus: A Prospective Multicenter Cohort Study
por: Roth, Jan A, et al.
Publicado: (2020)

Adherence as a Predictor of the Development of Class-Specific Resistance Mutations: The Swiss HIV Cohort Study
por: von Wyl, Viktor, et al.
Publicado: (2013)

Data linkage to evaluate the long-term risk of HIV infection in individuals seeking post-exposure prophylaxis
por: Hovaguimian, Frédérique, et al.
Publicado: (2021)

Loss to follow-up of HIV-infected women after delivery: The Swiss HIV Cohort Study and the Swiss Mother and Child HIV Cohort Study
por: Aebi-Popp, Karoline, et al.
Publicado: (2014)

Life expectancy in HIV-positive persons in Switzerland: matched comparison with general population
por: Gueler, Aysel, et al.
Publicado: (2017)

CD4/CD8 ratio and CD8 counts predict CD4 response in HIV-1-infected drug naive and in patients on cART
por: Sauter, Rafael, et al.
Publicado: (2016)

Distinct, IgG1-driven antibody response landscapes demarcate individuals with broadly HIV-1 neutralizing activity
por: Kadelka, Claus, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_jvemnvlahr0u4kl573skd4hu5c