The Mechanisms of PD-L1 Regulation in Non-Small-Cell Lung Cancer (NSCLC): Which Are the Involved Players?

SIMPLE SUMMARY: Immunotherapy against PD-1/PD-L1 dramatically improved outcomes in non-small cell lung cancer patients. These treatments are more effective the higher the expression of PD-L1 on tumor cells, reported as tumor proportion score. However, PD-L1 expression can be highly variable, dependi...

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Detalles Bibliográficos
Autores principales: Lamberti, Giuseppe, Sisi, Monia, Andrini, Elisa, Palladini, Arianna, Giunchi, Francesca, Lollini, Pier-Luigi, Ardizzoni, Andrea, Gelsomino, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692442/
https://www.ncbi.nlm.nih.gov/pubmed/33114576
http://dx.doi.org/10.3390/cancers12113129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692442/
https://www.ncbi.nlm.nih.gov/pubmed/33114576
http://dx.doi.org/10.3390/cancers12113129

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