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Overexpression of corticotropin-releasing factor in intestinal mucosal eosinophils is associated with clinical severity in Diarrhea-Predominant Irritable Bowel Syndrome

Corticotropin-releasing factor (CRF) has been identified in intestinal mucosal eosinophils and associated with psychological stress and gut dysfunction. Irritable bowel syndrome (IBS) is commonly characterized by altered intestinal motility, immune activation, and increased gut barrier permeability...

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Detalles Bibliográficos
Autores principales: Salvo-Romero, Eloísa, Martínez, Cristina, Lobo, Beatriz, Rodiño-Janeiro, Bruno K., Pigrau, Marc, Sánchez-Chardi, Alejandro D., González-Castro, Ana M., Fortea, Marina, Pardo-Camacho, Cristina, Nieto, Adoración, Expósito, Elba, Guagnozzi, Danila, Rodríguez-Urrutia, Amanda, de Torres, Inés, Farré, Ricard, Azpiroz, Fernando, Alonso-Cotoner, Carmen, Santos, Javier, Vicario, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692489/
https://www.ncbi.nlm.nih.gov/pubmed/33244004
http://dx.doi.org/10.1038/s41598-020-77176-x