Activity-dependent interdomain dynamics of matrix metalloprotease-1 on fibrin

The roles of protein conformational dynamics and allostery in function are well-known. However, the roles that interdomain dynamics have in function are not entirely understood. We used matrix metalloprotease-1 (MMP1) as a model system to study the relationship between interdomain dynamics and activ...

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Detalles Bibliográficos
Autores principales: Kumar, Lokender, Planas-Iglesias, Joan, Harms, Chase, Kamboj, Sumaer, Wright, Derek, Klein-Seetharaman, Judith, Sarkar, Susanta K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692495/
https://www.ncbi.nlm.nih.gov/pubmed/33244162
http://dx.doi.org/10.1038/s41598-020-77699-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692495/
https://www.ncbi.nlm.nih.gov/pubmed/33244162
http://dx.doi.org/10.1038/s41598-020-77699-3

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