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Activity-dependent interdomain dynamics of matrix metalloprotease-1 on fibrin
The roles of protein conformational dynamics and allostery in function are well-known. However, the roles that interdomain dynamics have in function are not entirely understood. We used matrix metalloprotease-1 (MMP1) as a model system to study the relationship between interdomain dynamics and activ...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692495/ https://www.ncbi.nlm.nih.gov/pubmed/33244162 http://dx.doi.org/10.1038/s41598-020-77699-3 |