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A Proline-Based Tectons and Supramolecular Synthons for Drug Design 2.0: A Case Study of ACEI

Proline is a unique, endogenous amino acid, prevalent in proteins and essential for living organisms. It is appreciated as a tecton for the rational design of new bio-active substances. Herein, we present a short overview of the subject. We analyzed 2366 proline-derived structures deposited in the C...

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Detalles Bibliográficos
Autores principales: Bojarska, Joanna, Remko, Milan, Breza, Martin, Madura, Izabela, Fruziński, Andrzej, Wolf, Wojciech M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692516/
https://www.ncbi.nlm.nih.gov/pubmed/33114370
http://dx.doi.org/10.3390/ph13110338