A Review of the Important Role of CYP2D6 in Pharmacogenomics

Cytochrome P450 2D6 (CYP2D6) is a critical pharmacogene involved in the metabolism of ~20% of commonly used drugs across a broad spectrum of medical disciplines including psychiatry, pain management, oncology and cardiology. Nevertheless, CYP2D6 is highly polymorphic with single-nucleotide polymorph...

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Detalles Bibliográficos
Autores principales: Taylor, Christopher, Crosby, Ian, Yip, Vincent, Maguire, Peter, Pirmohamed, Munir, Turner, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692531/
https://www.ncbi.nlm.nih.gov/pubmed/33143137
http://dx.doi.org/10.3390/genes11111295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692531/
https://www.ncbi.nlm.nih.gov/pubmed/33143137
http://dx.doi.org/10.3390/genes11111295

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