Rare VPS35 A320V Variant in Taiwanese Parkinson’s Disease Indicates Disrupted CI-MPR Sorting and Impaired Mitochondrial Morphology

Sequence variants in vacuolar protein sorting 35 (VPS35) have been reported to be associated with Parkinson’s disease (PD). To investigate if the genetic variants in VPS35 contribute to Taiwanese PD, VPS35 cDNA fragments from 62 patients with PD were sequenced. A cohort of PD (n = 560) and ethnicall...

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Detalles Bibliográficos
Autores principales: Wu, Yih-Ru, Lin, Chih-Hsin, Chao, Chih-Ying, Chang, Chia-Wen, Chen, Chiung-Mei, Lee-Chen, Guey-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692537/
https://www.ncbi.nlm.nih.gov/pubmed/33120894
http://dx.doi.org/10.3390/brainsci10110783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692537/
https://www.ncbi.nlm.nih.gov/pubmed/33120894
http://dx.doi.org/10.3390/brainsci10110783

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