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Activation of p38 MAPK participates in the sulbactam-induced cerebral ischemic tolerance mediated by glial glutamate transporter-1 upregulation in rats

Our previous studies have shown that sulbactam can play a neuroprotection role in hippocampal neurons by upregulating the expression and function of glial glutamate transporter-1 (GLT-1) during ischemic insult. Here, using rat global cerebral ischemia model, we studied in vivo the role of p38 mitoge...

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Detalles Bibliográficos
Autores principales: Xian, Xiao-Hui, Gao, Jun-Xia, Qi, Jie, Fan, Shu-Juan, Zhang, Min, Li, Wen-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692545/
https://www.ncbi.nlm.nih.gov/pubmed/33244020
http://dx.doi.org/10.1038/s41598-020-77583-0