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Activation of p38 MAPK participates in the sulbactam-induced cerebral ischemic tolerance mediated by glial glutamate transporter-1 upregulation in rats
Our previous studies have shown that sulbactam can play a neuroprotection role in hippocampal neurons by upregulating the expression and function of glial glutamate transporter-1 (GLT-1) during ischemic insult. Here, using rat global cerebral ischemia model, we studied in vivo the role of p38 mitoge...
Autores principales: | Xian, Xiao-Hui, Gao, Jun-Xia, Qi, Jie, Fan, Shu-Juan, Zhang, Min, Li, Wen-Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692545/ https://www.ncbi.nlm.nih.gov/pubmed/33244020 http://dx.doi.org/10.1038/s41598-020-77583-0 |
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