Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin

NF-Y is a transcription factor (TF) comprising three subunits (NF-YA, NF-YB, NF-YC) that binds with high specificity to the CCAAT sequence, a widespread regulatory element in gene promoters of prosurvival, cell-cycle-promoting, and metabolic genes. Tumor cells undergo “metabolic rewiring” through ov...

Descripción completa

Detalles Bibliográficos
Autores principales: Nardone, Valentina, Chaves-Sanjuan, Antonio, Lapi, Michela, Airoldi, Cristina, Saponaro, Andrea, Pasqualato, Sebastiano, Dolfini, Diletta, Camilloni, Carlo, Bernardini, Andrea, Gnesutta, Nerina, Mantovani, Roberto, Nardini, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692634/
https://www.ncbi.nlm.nih.gov/pubmed/33138093
http://dx.doi.org/10.3390/cells9112370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692634/
https://www.ncbi.nlm.nih.gov/pubmed/33138093
http://dx.doi.org/10.3390/cells9112370

Ejemplares similares