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Regulation of CAR and PXR Expression in Health and Disease

Pregnane X receptor (PXR, NR1I2) and constitutive androstane receptor (CAR, NR1I3) are members of the nuclear receptor superfamily that mainly act as ligand-activated transcription factors. Their functions have long been associated with the regulation of drug metabolism and disposition, and it is no...

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Detalles Bibliográficos
Autores principales: Daujat-Chavanieu, Martine, Gerbal-Chaloin, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692647/
https://www.ncbi.nlm.nih.gov/pubmed/33142929
http://dx.doi.org/10.3390/cells9112395