Cargando…

Magnesium Absorption in Intestinal Cells: Evidence of Cross-Talk between EGF and TRPM6 and Novel Implications for Cetuximab Therapy

Hypomagnesemia is very commonly observed in cancer patients, most frequently in association with therapy with cetuximab (CTX), a monoclonal antibody targeting the epithelial growth factor receptor (EGFR). CTX-induced hypomagnesemia has been ascribed to renal magnesium (Mg) wasting. Here, we sought t...

Descripción completa

Detalles Bibliográficos
Autores principales: Pietropaolo, Giuseppe, Pugliese, Daniela, Armuzzi, Alessandro, Guidi, Luisa, Gasbarrini, Antonio, Rapaccini, Gian Lodovico, Wolf, Federica I., Trapani, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692710/
https://www.ncbi.nlm.nih.gov/pubmed/33114586
http://dx.doi.org/10.3390/nu12113277