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Magnesium Absorption in Intestinal Cells: Evidence of Cross-Talk between EGF and TRPM6 and Novel Implications for Cetuximab Therapy
Hypomagnesemia is very commonly observed in cancer patients, most frequently in association with therapy with cetuximab (CTX), a monoclonal antibody targeting the epithelial growth factor receptor (EGFR). CTX-induced hypomagnesemia has been ascribed to renal magnesium (Mg) wasting. Here, we sought t...
Autores principales: | Pietropaolo, Giuseppe, Pugliese, Daniela, Armuzzi, Alessandro, Guidi, Luisa, Gasbarrini, Antonio, Rapaccini, Gian Lodovico, Wolf, Federica I., Trapani, Valentina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692710/ https://www.ncbi.nlm.nih.gov/pubmed/33114586 http://dx.doi.org/10.3390/nu12113277 |
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