Aromatic Linkers Unleash the Antiproliferative Potential of 3‐Chloropiperidines Against Pancreatic Cancer Cells

In this study, we describe the synthesis and biological evaluation of a set of bis‐3‐chloropiperidines (B−CePs) containing rigid aromatic linker structures. A modification of the synthetic strategy also enabled the synthesis of a pilot tris‐3‐chloropiperidine (Tri‐CeP) bearing three reactive meta‐ch...

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Detalles Bibliográficos
Autores principales: Helbing, Tim, Carraro, Caterina, Francke, Alexander, Sosic, Alice, De Franco, Michele, Gandin, Valentina, Göttlich, Richard, Gatto, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692949/
https://www.ncbi.nlm.nih.gov/pubmed/32744774
http://dx.doi.org/10.1002/cmdc.202000457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692949/
https://www.ncbi.nlm.nih.gov/pubmed/32744774
http://dx.doi.org/10.1002/cmdc.202000457

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