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PODO447: a novel antibody to a tumor-restricted epitope on the cancer antigen podocalyxin

BACKGROUND: The success of new targeted cancer therapies has been dependent on the identification of tumor-specific antigens. Podocalyxin (Podxl) is upregulated on tumors with high metastatic index and its presence is associated with poor outcome, thus emerging as an important prognostic and theragn...

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Detalles Bibliográficos
Autores principales: Canals Hernaez, Diana, Hughes, Michael R, Dean, Pamela, Bergqvist, Peter, Samudio, Ismael, Blixt, Ola, Wiedemeyer, Katharina, Li, Yicong, Bond, Chris, Cruz, Eric, Köbel, Martin, Gilks, Blake, Roskelley, Calvin D, McNagny, Kelly M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692987/
https://www.ncbi.nlm.nih.gov/pubmed/33243933
http://dx.doi.org/10.1136/jitc-2020-001128