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PODO447: a novel antibody to a tumor-restricted epitope on the cancer antigen podocalyxin
BACKGROUND: The success of new targeted cancer therapies has been dependent on the identification of tumor-specific antigens. Podocalyxin (Podxl) is upregulated on tumors with high metastatic index and its presence is associated with poor outcome, thus emerging as an important prognostic and theragn...
Autores principales: | Canals Hernaez, Diana, Hughes, Michael R, Dean, Pamela, Bergqvist, Peter, Samudio, Ismael, Blixt, Ola, Wiedemeyer, Katharina, Li, Yicong, Bond, Chris, Cruz, Eric, Köbel, Martin, Gilks, Blake, Roskelley, Calvin D, McNagny, Kelly M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7692987/ https://www.ncbi.nlm.nih.gov/pubmed/33243933 http://dx.doi.org/10.1136/jitc-2020-001128 |
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