Roles of Farnesyl-Diphosphate Farnesyltransferase 1 in Tumour and Tumour Microenvironments

Farnesyl-diphosphate farnesyltransferase 1 (FDFT1, squalene synthase), a membrane-associated enzyme, synthesizes squalene via condensation of two molecules of farnesyl pyrophosphate. Accumulating evidence has noted that FDFT1 plays a critical role in cancer, particularly in metabolic reprogramming,...

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Detalles Bibliográficos
Autores principales: Ha, Nguyen Thi, Lee, Chang Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693003/
https://www.ncbi.nlm.nih.gov/pubmed/33113804
http://dx.doi.org/10.3390/cells9112352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693003/
https://www.ncbi.nlm.nih.gov/pubmed/33113804
http://dx.doi.org/10.3390/cells9112352

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