Olaparib Synergizes the Anticancer Activity of Daunorubicin via Interaction with AKR1C3

SAMPLE SUMMARY: Anthracyclines (ANT) are anti-tumor agents frequently used for the treatment of various cancers. Unfortunately, their clinical success is overshadowed by the emergence of drug resistance. Metabolism by carbonyl reducing enzymes (CREs) represents a critical mechanism of ANT resistance...

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Detalles Bibliográficos
Autores principales: Tavares, Tássia S., Hofman, Jakub, Lekešová, Alžběta, Želazková, Jana, Wsól, Vladimír
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693014/
https://www.ncbi.nlm.nih.gov/pubmed/33114555
http://dx.doi.org/10.3390/cancers12113127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693014/
https://www.ncbi.nlm.nih.gov/pubmed/33114555
http://dx.doi.org/10.3390/cancers12113127

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