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Olaparib Synergizes the Anticancer Activity of Daunorubicin via Interaction with AKR1C3
SAMPLE SUMMARY: Anthracyclines (ANT) are anti-tumor agents frequently used for the treatment of various cancers. Unfortunately, their clinical success is overshadowed by the emergence of drug resistance. Metabolism by carbonyl reducing enzymes (CREs) represents a critical mechanism of ANT resistance...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693014/ https://www.ncbi.nlm.nih.gov/pubmed/33114555 http://dx.doi.org/10.3390/cancers12113127 |