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Fine‐mapping and QTL tissue‐sharing information improves the reliability of causal gene identification

The integration of transcriptomic studies and genome‐wide association studies (GWAS) via imputed expression has seen extensive application in recent years, enabling the functional characterization and causal gene prioritization of GWAS loci. However, the techniques for imputing transcriptomic traits...

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Detalles Bibliográficos
Autores principales: Barbeira, Alvaro N., Melia, Owen J., Liang, Yanyu, Bonazzola, Rodrigo, Wang, Gao, Wheeler, Heather E., Aguet, François, Ardlie, Kristin G., Wen, Xiaoquan, Im, Hae K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693040/
https://www.ncbi.nlm.nih.gov/pubmed/32964524
http://dx.doi.org/10.1002/gepi.22346