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A thermostable DNA primase‐polymerase from a mobile genetic element involved in defence against environmental DNA

Primase‐polymerases (Ppol) are one of the few enzymes able to start DNA synthesis on ssDNA templates. The role of Thermus thermophilus HB27 Ppol, encoded along a putative helicase (Hel) within a mobile genetic element (ICETh2), has been studied. A mutant lacking Ppol showed no effects on the replica...

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Detalles Bibliográficos
Autores principales: García‐Quintans, Nieves, Baquedano, Ignacio, Blesa, Alba, Verdú, Carlos, Berenguer, José, Mencía, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693054/
https://www.ncbi.nlm.nih.gov/pubmed/32830367
http://dx.doi.org/10.1111/1462-2920.15207