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A thermostable DNA primase‐polymerase from a mobile genetic element involved in defence against environmental DNA
Primase‐polymerases (Ppol) are one of the few enzymes able to start DNA synthesis on ssDNA templates. The role of Thermus thermophilus HB27 Ppol, encoded along a putative helicase (Hel) within a mobile genetic element (ICETh2), has been studied. A mutant lacking Ppol showed no effects on the replica...
Autores principales: | García‐Quintans, Nieves, Baquedano, Ignacio, Blesa, Alba, Verdú, Carlos, Berenguer, José, Mencía, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693054/ https://www.ncbi.nlm.nih.gov/pubmed/32830367 http://dx.doi.org/10.1111/1462-2920.15207 |
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