Tissue‐specific deletion of mouse basolateral uniporter LAT4 (Slc43a2) reveals its crucial role in small intestine and kidney amino acid transport

KEY POINTS: LAT4 is a broadly expressed uniporter selective for essential branched chain amino acids, methionine and phenylalanine, which are involved in epithelial transport. Its global deletion leads to an early malnutrition‐like phenotype and death within 10 days after birth. Here, we tested the...

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Detalles Bibliográficos
Autores principales: Rajendran, Anuradha, Poncet, Nadège, Oparija‐Rogenmozere, Lalita, Herzog, Brigitte, Verrey, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Endocrine, Nutrition and Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693055/
https://www.ncbi.nlm.nih.gov/pubmed/32841365
http://dx.doi.org/10.1113/JP280234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693055/
https://www.ncbi.nlm.nih.gov/pubmed/32841365
http://dx.doi.org/10.1113/JP280234

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