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The malate–aspartate shuttle (Borst cycle): How it started and developed into a major metabolic pathway
This article presents a personal and critical review of the history of the malate–aspartate shuttle (MAS), starting in 1962 and ending in 2020. The MAS was initially proposed as a route for the oxidation of cytosolic NADH by the mitochondria in Ehrlich ascites cell tumor lacking other routes, and to...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley & Sons, Inc.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693074/ https://www.ncbi.nlm.nih.gov/pubmed/32916028 http://dx.doi.org/10.1002/iub.2367 |