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Distinct features of calcium handling and β‐adrenergic sensitivity in heart failure with preserved versus reduced ejection fraction

KEY POINTS: Heart failure (HF), the leading cause of death in developed countries, occurs in the setting of reduced (HFrEF) or preserved (HFpEF) ejection fraction. Unlike HFrEF, there are no effective treatments for HFpEF, which accounts for ∼50% of heart failure. Abnormal intracellular calcium dyna...

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Detalles Bibliográficos
Autores principales: Kilfoil, Peter J., Lotteau, Sabine, Zhang, Rui, Yue, Xin, Aynaszyan, Stephan, Solymani, Ryan E., Cingolani, Eugenio, Marbán, Eduardo, Goldhaber, Joshua I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693093/
https://www.ncbi.nlm.nih.gov/pubmed/32829489
http://dx.doi.org/10.1113/JP280425