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Expression levels of FBXW7 and MDM2 E3 ubiquitin ligases and their c-Myc and p53 substrates in patients with dysplastic nevi or melanoma

E3 ubiquitin ligases are of interest as drug targets due to their involvement in the regulation of the functions and interactions of several proteins. Various E3 ligase complexes are considered oncogenes or tumor suppressors associated with the development of melanoma. These proteins regulate the fu...

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Detalles Bibliográficos
Autores principales: Mozuraitiene, Julija, Gudleviciene, Zivile, Vincerzevskiene, Ieva, Laurinaviciene, Aida, Pamedys, Justinas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693127/
https://www.ncbi.nlm.nih.gov/pubmed/33262829
http://dx.doi.org/10.3892/ol.2020.12298