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Prostate Cancer Proliferation Is Affected by the Subcellular Localization of MCT2 and Accompanied by Significant Peroxisomal Alterations

SIMPLE SUMMARY: Fatty acid β-oxidation is a dominant bioenergetic pathway in prostate cancer. It has recently been suggested that the specific targeting of monocarboxylate transporter 2 (MCT2) to peroxisomes contributed to an increase in β-oxidation rates and maintenance of the redox balance in pros...

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Detalles Bibliográficos
Autores principales: Valença, Isabel, Ferreira, Ana Rita, Correia, Marcelo, Kühl, Sandra, van Roermund, Carlo, Waterham, Hans R., Máximo, Valdemar, Islinger, Markus, Ribeiro, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693163/
https://www.ncbi.nlm.nih.gov/pubmed/33121137
http://dx.doi.org/10.3390/cancers12113152