Homologation of the Fischer Indolization: A Quinoline Synthesis via Homo‐Diaza‐Cope Rearrangement

We disclose a new Brønsted acid promoted quinoline synthesis, proceeding via homo‐diaza‐Cope rearrangement of N‐aryl‐N′‐cyclopropyl hydrazines. Our strategy can be considered a homologation of Fischer's classical indole synthesis and delivers 6‐membered N‐heterocycles, including previously inac...

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Detalles Bibliográficos
Autores principales: Gerosa, Gabriela Guillermina, Schwengers, Sebastian Armin, Maji, Rajat, De, Chandra Kanta, List, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693176/
https://www.ncbi.nlm.nih.gov/pubmed/32621795
http://dx.doi.org/10.1002/anie.202005798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693176/
https://www.ncbi.nlm.nih.gov/pubmed/32621795
http://dx.doi.org/10.1002/anie.202005798

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