Replacement of the Cobalt Center of Vitamin B(12) by Nickel: Nibalamin and Nibyric Acid Prepared from Metal‐Free B(12) Ligands Hydrogenobalamin and Hydrogenobyric Acid

The (formal) replacement of Co in cobalamin (Cbl) by Ni(II) generates nibalamin (Nibl), a new transition‐metal analogue of vitamin B(12). Described here is Nibl, synthesized by incorporation of a Ni(II) ion into the metal‐free B(12) ligand hydrogenobalamin (Hbl), itself prepared from hydrogenobyric...

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Detalles Bibliográficos
Autores principales: Kieninger, Christoph, Wurst, Klaus, Podewitz, Maren, Stanley, Maria, Deery, Evelyne, Lawrence, Andrew D., Liedl, Klaus R., Warren, Martin J., Kräutler, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693184/
https://www.ncbi.nlm.nih.gov/pubmed/32686888
http://dx.doi.org/10.1002/anie.202008407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693184/
https://www.ncbi.nlm.nih.gov/pubmed/32686888
http://dx.doi.org/10.1002/anie.202008407

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