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Model‐dependent contributions of FXII and FXI to venous thrombosis in mice

BACKGROUND: The intrinsic pathway factors (F) XII and FXI have been shown to contribute to thrombosis in animal models. We assessed the role of FXII and FXI in venous thrombosis in three distinct mouse models. METHODS: Venous thrombosis was assessed in mice genetically deficient for either FXII or F...

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Detalles Bibliográficos
Autores principales: Grover, Steven P., Olson, Tatianna M., Cooley, Brian C., Mackman, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693194/
https://www.ncbi.nlm.nih.gov/pubmed/33094904
http://dx.doi.org/10.1111/jth.15037