Phospholipase D1 inhibition sensitizes glioblastoma to temozolomide and suppresses its tumorigenicity

Resistance of glioblastoma to the chemotherapeutic compound temozolomide is associated with the presence of glioblastoma stem cells in glioblastoma and is a key obstacle for the poor prognosis of glioblastoma. Here, we show that phospholipase D1 is elevated in CD44(High) glioblastoma stem cells and...

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Detalles Bibliográficos
Autores principales: Kang, Dong Woo, Hwang, Won Chan, Noh, Yu Na, Park, Kang Seo, Min, Do Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693208/
https://www.ncbi.nlm.nih.gov/pubmed/32725633
http://dx.doi.org/10.1002/path.5519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693208/
https://www.ncbi.nlm.nih.gov/pubmed/32725633
http://dx.doi.org/10.1002/path.5519

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