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Mitochondrial ROS prime the hyperglycemic shift from apoptosis to necroptosis
We have previously identified a shift from TNF-α-induced apoptosis to necroptosis that occurs under hyperglycemic conditions. This shift involves the downregulation or silencing of caspases and concurrent upregulation of necroptotic proteins leading to activation of the necrosome. In addition, under...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693268/ https://www.ncbi.nlm.nih.gov/pubmed/33298902 http://dx.doi.org/10.1038/s41420-020-00370-3 |