TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis

Cytomegaloviruses all encode the viral inhibitor of caspase-8-induced apoptosis (vICA). After binding to this initiator caspase, vICA blocks caspase-8 proteolytic activity and ability to activate caspase-3 and/or caspase-7. In this manner, vICA has long been known to prevent apoptosis triggered via...

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Detalles Bibliográficos
Autores principales: Mandal, Pratyusha, McCormick, A. Louise, Mocarski, Edward S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693317/
https://www.ncbi.nlm.nih.gov/pubmed/33126536
http://dx.doi.org/10.3390/v12111221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693317/
https://www.ncbi.nlm.nih.gov/pubmed/33126536
http://dx.doi.org/10.3390/v12111221

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