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Arginase 1 is involved in lacrimal hyposecretion in male NOD mice, a model of Sjögren's syndrome, regardless of dacryoadenitis status

KEY POINTS: Few reports have explored the possibility of involvement of non‐inflammatory factors in lacrimal hyposecretion in Sjögren's syndrome (SS). RNA‐sequencing analysis revealed that only four genes, including arginase 1, were downregulated in the lacrimal gland of SS model male mice (NOD...

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Detalles Bibliográficos
Autores principales: Ohno, Yuta, Satoh, Keitaro, Shitara, Akiko, Into, Takeshi, Kashimata, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693353/
https://www.ncbi.nlm.nih.gov/pubmed/32780506
http://dx.doi.org/10.1113/JP280090