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Amyloid-β Peptide Impact on Synaptic Function and Neuroepigenetic Gene Control Reveal New Therapeutic Strategies for Alzheimer’s Disease
Amyloid-β (Aβ) peptides can form protease-resistant aggregates within and outside of neurons. Accumulation of these aggregates is a hallmark of Alzheimer’s disease (AD) neuropathology and contributes to devastating cognitive deficits associated with this disorder. The primary etiological factor for...
Autores principales: | Karisetty, Bhanu Chandra, Bhatnagar, Akanksha, Armour, Ellen M., Beaver, Mariah, Zhang, Haolin, Elefant, Felice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693454/ https://www.ncbi.nlm.nih.gov/pubmed/33304239 http://dx.doi.org/10.3389/fnmol.2020.577622 |
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